Highlights included putting a fatwa on tv host Rove McManus, John asking the Grand Dragon of the KKK if he can join despite the fact he's Jewish, removing a curse from the Australian soccer team, watching possessed Haitians bite the testicles of a live goat, being chased by men armed machine guns and getting John's demons cast out by exorcist Rev. Bob Larsen.

John Safran vs God was also where John first meet Father Bob McGuire who would later become his long time radio partner.